Miscarriage in MPN

If you are a woman with a myeloproliferative neoplasm (MPN), a type of blood disorder, you may have heard that you have a higher chance of losing your pregnancy before the 20th week. This is called a miscarriage, and it can be a very painful and traumatic experience for anyone who goes through it.

There are many possible causes of miscarriage, such as age, genetics, chronic diseases, and other complications. Unfortunately, not much is known about how MPNs affect pregnancy outcomes because there is not enough research on this topic. However, some studies suggest that women with MPNs may have more difficulties conceiving and carrying a baby to term than women without MPNs.

This does not mean that you cannot have a healthy pregnancy if you have an MPN. But it does mean that you need to take extra care of yourself and your baby before and during your pregnancy.

You should talk to your MPN healthcare team before you try to get pregnant and make sure you have a comprehensive checkup and follow-up.

You should also stop taking certain medications such as hydroxycarbamide and anagrelide at least six months before you plan to conceive. These drugs can harm your baby's development and increase the risk of miscarriage in MPN.

If you have had one or more miscarriages in the past, you may feel hopeless and angry. You may feel isolated or unsupported by your partner, friends, or family. You may wonder why this happened to you and what you can do to prevent it from happening again.

If you think you have had a miscarriage, you should contact your GP and hematologist as soon as possible. They can confirm the diagnosis and provide you with medical care and emotional support. They can also help you adjust your medication after the miscarriage if needed to protect your health.